Drugs / Loxoprofen
Loxoprofen
also known as
loxoprofen sodium · Loxonin · Loxonine tab. · LOXONNIN · Loxoprofen acid · loxoprofen patch · loxoprofen tablet · Loxoprofene · +3 more
Trials 10
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials | ||||||
| Phase 2 | NCT02602353 | Oct → Dec 2015 | — | Lead Chemical Co., Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT01922466 | Jul 2013 → Mar 2014 | — | Kyunghee University Medical Center | Completed | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT02831569 | Jul → Oct 2016 | — | Boehringer Ingelheim | Completed | No outcome recorded |
| Phase 3 | NCT00141154 | Oct 2004 → ? | — | Viatris Inc. | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT03800797 | May → Dec 2015 | ankylosing spondylitis | Sun Yat-sen University | Completed | No outcome recorded |
| Phase not applicable5 trials | ||||||
| — | NCT07591220 | Jun 2026 → Dec 2027 expected | — | Beijing Tiantan Hospital | Not yet recruiting | No outcome recorded |
| — | NCT07591207 | Jun 2026 → Dec 2027 expected | gallbladder disorder | Beijing Tiantan Hospital | Recruiting | No outcome recorded |
| — | NCT07378059 | Dec 2025 → Sep 2027 expected | herpes zoster | Beijing Tiantan Hospital | Recruiting | No outcome recorded |
| — | NCT04611685 | Oct 2020 → Oct 2021 | pituitary gland adenoma | Peking Union Medical College Hospital | Unknown | No outcome recorded |
| — | NCT02983747 | Nov 2019 → Dec 2022 | — | Shanghai Changzheng Hospital | Unknown | No outcome recorded |
| Comparator or background therapy9 trials | ||||||
| Phase 1 | NCT00676117 Comparator | Apr → Jul 2008 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT06047483 Comparator | Oct → Dec 2023 | — | Jiangsu HengRui Medicine Co., Ltd. | Unknown | No outcome recorded |
| Phase 2 | NCT02467504 Comparator | Jul 2015 → Jan 2017 | rheumatoid arthritis | Peking University People's Hospital | Completed | No outcome recorded |
| Phase 2 | NCT01491321 Background | Apr 2011 → Mar 2012 | chronic pain syndrome | Kyunghee University Medical Center | Unknown | No outcome recorded |
| Phase 3 | NCT03386149 Comparator | Dec 2017 → Dec 2019 | lumbar disk disease | Kyunghee University Medical Center | Completed | Met primary |
| Phase 3 | NCT02616068 Comparator | Oct 2015 → Dec 2016 | — | Daiichi Sankyo | Completed | No outcome recorded |
| Phase 3 | NCT01779271 Comparator | Jan 2013 → Mar 2016 | respiratory tract infectious disorder | Daewon Pharmaceutical Co., Ltd. | Completed | Met primary |
| Phase 4 | NCT00994461 Comparator | Nov 2009 → Apr 2010 | — | Viatris Inc. | Completed | Met primary |
| — | NCT02384928 Comparator | Sep 2015 → Jan 2017 | lumbar disk disease, sciatica | Jaseng Medical Foundation | Completed | No outcome recorded |
News releases announcing trial results or a regulatory action · 2
| Date | Issuer | Release |
|---|---|---|
| 2008-03-12 | Daiichi Sankyo | Regulatory The Percutaneous Absorption-Type Analgesic and Anti-inflammatory Drug Loxonin(R)Tape 50mg/100mg Receives Approval for Manufacture and Marketing daiichisankyo.com ↗
The Percutaneous Absorption-Type Analgesic and Anti-inflammatory Drug Loxonin(R)Tape 50mg/100mg Receives Approval for Manufacture and Marketing |
| 2006-01-23 | Daiichi Sankyo | Regulatory The Percutaneous Absorption-Type Analgesic and Anti-inflammatory Drug Loxonin Poultice 100mg Receives Approval for Manufacture daiichisankyo.com ↗
The Percutaneous Absorption-Type Analgesic and Anti-inflammatory Drug Loxonin Poultice 100mg Receives Approval for Manufacture |
All press releases naming this drug 5 releases
Evidence & citations 14 cited values
Every value below carries the sentence it was read from. 22 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | loxoprofen | “Loxoprofen (po.) for routine use during the first 3 postop. days.” NCT04611685 ↗14“Ingredient : Loxoprofen Sodium 68.1mg (Loxoprofen 60mg)” NCT03386149 ↗ “loxoprofen sodium (Drug class: NSAIDs)” NCT02384928 ↗ |
| Known as | Loxonin | “Loxonin® (loxoprofen sodium 60 mg - Daiichi-Sankyo - control group)” NCT02616068 ↗ |
| Known as | Loxonine tab. | “Product name : Loxonine tab. Manufacturer : Dong Wha Pharm. Co., Ltd Ingredient : Loxoprofen Sodium 68.1mg (Loxoprofen 60mg)” NCT03386149 ↗ |
| Known as | LOXONNIN | “Loxoprofen Sodium tablets(LOXONNIN®, DAICHI SANKYO PHARMACEUTIAL (SHANGHAI) Co . Ltd .)，P.O., 60mg, three times a day” NCT02983747 ↗ |
| Known as | Loxoprofen acid | ChEMBL registry synonym — accepted as the source's own label CHEMBL19299 ↗ |
| Known as | loxoprofen patch | “Therefore, we aimed at evaluating the efficacy and safety of loxoprofen patch (LX-P) in the treatment of patients with posttraumatic pain.” PMID 30839430 ↗ Jul 2019 |
| Known as | loxoprofen sodium | “Efficacy and safety of loxoprofen sodium topical patch for the treatment of pain in patients with minor acute traumatic limb injuries in Brazil: a randomized, double-blind,...” PMID 30839430 ↗ Jul 20197“Product name : Loxonine tab. Manufacturer : Dong Wha Pharm. Co., Ltd Ingredient : Loxoprofen Sodium 68.1mg (Loxoprofen 60mg)” NCT03386149 ↗ “loxoprofen sodium (loxoprofen), a pro-drug in the propionic acid class of nonselective NSAIDs” PMID 23216412 ↗ Dec 2012 “loxoprofen sodium (Drug class: NSAIDs)” NCT02384928 ↗ |
| Known as | loxoprofen tablet | “Patients were assigned to active LX-P or to loxoprofen tablet (LX-T), and pain intensity was measured based on a visual analog scale score variation after 7 days of treatment.” PMID 30839430 ↗ Jul 2019 |
| Known as | Loxoprofene | ChEMBL registry synonym — accepted as the source's own label CHEMBL19299 ↗ |
| Known as | Loxoprofeno | ChEMBL registry synonym — accepted as the source's own label CHEMBL19299 ↗ |
| Known as | LX-P | “Therefore, we aimed at evaluating the efficacy and safety of loxoprofen patch (LX-P) in the treatment of patients with posttraumatic pain.” PMID 30839430 ↗ Jul 2019 |
| Known as | LX-T | “Patients were assigned to active LX-P or to loxoprofen tablet (LX-T), and pain intensity was measured based on a visual analog scale score variation after 7 days of treatment.” PMID 30839430 ↗ Jul 2019 |
| Modality | Small molecule | “loxoprofen sodium (loxoprofen), a pro-drug in the propionic acid class of nonselective NSAIDs” PMID 23216412 ↗ Dec 2012 |
| Route | Oral | “repeated oral administration” NCT00676117 ↗ |