Drugs / DS-1040b
last change Feb 2020 re-read 9 days ago

DS-1040b

Small molecule

Developed for
ischemic stroke · thrombotic disease · pulmonary embolism
Investigated by
Daiichi Sankyo · Hammersmith Medicines Research

Trials 6

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT02647307 Feb → Jun 2016 — Daiichi Sankyo Completed No outcome recorded
Phase 1 NCT02560688 Dec 2015 → Mar 2016 — Daiichi Sankyo Completed No outcome recorded
Phase 1 NCT02071004 Jan → Feb 2014 ischemic stroke Daiichi Sankyo Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT02923115 Jun 2016 → Aug 2019 pulmonary embolism, thrombotic disease Daiichi Sankyo Completed No outcome recorded
Phase 1/2 NCT02586233 Sep 2015 → Aug 2019 ischemic stroke, thrombotic disease Daiichi Sankyo Completed No outcome recorded
Phase not applicable1 trial
— NCT03198715 Jul 2017 → Jan 2020 ischemic stroke Daiichi Sankyo Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as DS-1040b “Participants receive DS-1040b 0.6 mg by intravenous infusion over six hours” NCT03198715 ↗
6

NCT03198715 ↗

NCT02560688 ↗

NCT02586233 ↗

NCT02923115 ↗

NCT02647307 ↗

NCT02071004 ↗

Action Inhibit “inhibitor of activated thrombin-activatable fibrinolysis inhibitor” PMID 32106339 ↗ Feb 2020
Modality Small molecule “novel low-molecular-weight inhibitor” PMID 32106339 ↗ Feb 2020
Route Intravenous “IV of 6 mg given once over 30 minutes” NCT02071004 ↗