Drugs / DS-1040b
last change Feb 2020 re-read 2 minutes ago

DS-1040b

Small molecule

Developed for
ischemic stroke · thrombotic disease · pulmonary embolism
Investigated by
Daiichi Sankyo · Hammersmith Medicines Research

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT02647307 Feb → Jun 2016 Daiichi Sankyo Completed No outcome recorded
Phase 1 NCT02560688 Dec 2015 → Mar 2016 Daiichi Sankyo Completed No outcome recorded
Phase 1 NCT02071004 Jan → Feb 2014 ischemic stroke Daiichi Sankyo Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT02923115 Jun 2016 → Aug 2019 pulmonary embolism, thrombotic disease Daiichi Sankyo Completed No outcome recorded
Phase 1/2 NCT02586233 Sep 2015 → Aug 2019 ischemic stroke, thrombotic disease Daiichi Sankyo Completed No outcome recorded
Phase not applicable1 trial
NCT03198715 Jul 2017 → Jan 2020 ischemic stroke Daiichi Sankyo Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as DS-1040b “Participants receive DS-1040b 0.6 mg by intravenous infusion over six hours” NCT03198715
6

NCT02071004

NCT02647307

NCT02560688

NCT02923115

NCT02586233

NCT03198715

Action Inhibit inhibitor of activated thrombin-activatable fibrinolysis inhibitor” PMID 32106339 Feb 2020
Modality Small molecule “novel low-molecular-weight inhibitor” PMID 32106339 Feb 2020
Route Intravenous “IV of 6 mg given once over 30 minutes” NCT02071004