Drugs / Recombinant human plasma gelsolin
last change Dec 2025 re-read 3 minutes ago

Recombinant human plasma gelsolin

also known as Rhu-pGSN

Protein / enzyme biologic

Developed for
pneumonia · COVID-19 · decompression sickness
Investigated by
BioAegis Therapeutics Inc.

Trials 1

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT03466073 Aug 2018 → Apr 2019 pneumonia BioAegis Therapeutics Inc. Completed No outcome recorded
Comparator or background therapy2 trials
Phase 2 NCT06216366 Comparator Aug → Oct 2025 overdue decompression sickness BioAegis Therapeutics Inc. Active not recruiting No outcome recorded
Phase 2 NCT04358406 Comparator Jul 2020 → May 2021 COVID-19 BioAegis Therapeutics Inc. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Recombinant Human Plasma Gelsolin ClinicalTrials.gov intervention name — accepted as the source's own label NCT03466073 ↗
2

NCT06216366 ↗

NCT04358406 ↗

Known as Rhu-pGSN “Recombinant human plasma gelsolin (Rhu-pGSN)” NCT04358406 ↗
Modality Protein / enzyme biologic “Recombinant human plasma gelsolin lyophilized for reconstitution, reconstituted in sterile water” NCT03466073 ↗
Route Intravenous “Intravenous administration of recombinant human plasma gelsolin at 6 mg/kg” NCT03466073 ↗