Drugs / AJ1-11095
last change Jun 2026 re-read 3 minutes ago

AJ1-11095

targets JAK2 via inhibition

Developed for
myelofibrosis · primary myelofibrosis
Investigated by
Ajax Therapeutics, Inc.

Trials 1

20252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06343805 Oct 2024 → Oct 2026 expected myelofibrosis, primary myelofibrosis Ajax Therapeutics, Inc. Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2026-06-13 Eli Lilly and Company Results Lilly to present initial clinical data for first-in-class type II JAK2 inhibitor in patients with previously treated myelofibrosis at the 2026 EHA Annual Meeting lilly.com ↗
With an encouraging safety profile, meaningful spleen size reduction, symptom improvement, and decrease in underlying mutant disease burden, these data, while early, point to the potential to meaningfully impact treatment options for people with certain myeloproliferative neoplasms.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as AJ1-11095 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06343805 ↗
Action Inhibit “Type II JAK2 inhibitor” NCT06343805 ↗
Route Oral “taken orally by patients” NCT06343805 ↗
Target JAK2 “Type II JAK2 inhibitor” NCT06343805 ↗