Drugs / ZANSECIMAB
last change Oct 2020 re-read 2 minutes ago

ZANSECIMAB

also known as LY3127804

Monoclonal antibody targets ANGPT2 via inhibition

Developed for
cancer · COVID-19 · pneumonia
Investigated by
Eli Lilly and Company

Trials 2 · a red edge is where a trial was stopped

20162017201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02597036 Nov 2015 → Nov 2017 cancer Eli Lilly and Company Terminated No outcome recorded
Phase 21 trial
Phase 2 NCT04342897 Apr → Oct 2020 COVID-19, pneumonia Eli Lilly and Company Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as ZANSECIMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL4650486
Known as LY3127804 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02597036
1

NCT04342897

Action Inhibit “anti-angiopoietin-2 (Ang-2)” PMID 32741971 Aug 2020
1

“Angiopoietin-2 inhibitor” CHEMBL4650486

Modality Monoclonal antibody “anti-angiopoietin-2 (Ang-2) monoclonal antibodyPMID 32741971 Aug 2020
Route Intravenous “Administered IV” NCT02597036
Target ANGPT2 “Angiopoietin-2 inhibitor” CHEMBL4650486