Drugs / BB102
last change Apr 2026 re-read 3 minutes ago

BB102

targets FGFR4 via inhibition

Developed for
hepatocellular carcinoma · neoplasm
Investigated by
Broadenbio Ltd., Co.

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06258408 Dec 2022 → Dec 2026 expected neoplasm Broadenbio Ltd., Co. Recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT07239986 Dec 2025 → Jun 2027 expected hepatocellular carcinoma Broadenbio Ltd., Co. Not yet recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2026-04-22 Broadenbio Ltd., Co. Results 新一代FGFR4降解剂BB102——肝癌治疗新希望 broadenbio.com ↗
在4月21日的2026年美国肿瘤年会(AACR)上,伯汇生物首次报道了BB102作为FGFR4降解剂的作用机制及临床前研究结果。
2024-04-07 Broadenbio Ltd., Co. Results 伯汇生物两项临床前研究成果入选AACR 2024年会壁报展示 broadenbio.com ↗
在体外和体内实验中,BB102显著抑制多种实体瘤的增长,并能有效降低肿瘤组织中FGFR4的表达。

All press releases naming this drug 2 releases

DateIssuerRelease

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as BB102 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07239986 ↗
1

NCT06258408 ↗

Action Inhibit “a highly selective and potent FGFR4 inhibitor” NCT06258408 ↗
Route Oral “BB102 tablets will be administered orally once daily(QD).” NCT06258408 ↗
Target FGFR4 “a highly selective and potent FGFR4 inhibitor” NCT06258408 ↗