Drugs / PLOSARACETAM
last change Sep 2024 re-read 3 minutes ago

PLOSARACETAM

also known as ABBV-552 · SDI-118

Small molecule

Developed for
Alzheimer disease · major depressive disorder · subjective cognitive decline
Investigated by
AbbVie · Syndesi Therapeutics · KU Leuven · P1vital Limited

Trials 6

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT06278766 Feb → Apr 2024 — AbbVie Completed No outcome recorded
Phase 1 NCT05686980 Jan → Mar 2023 — AbbVie Completed No outcome recorded
Phase 1 NCT05199142 Sep 2021 → Mar 2022 subjective cognitive decline Syndesi Therapeutics Terminated No outcome recorded
Phase 1 NCT05212116 Sep 2021 → Mar 2022 major depressive disorder Syndesi Therapeutics Withdrawn No outcome recorded
Phase 1 NCT05486195 Mar → Jul 2019 cognitive disorder AbbVie Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT05771428 Jun 2023 → Aug 2024 Alzheimer disease AbbVie Completed Missed primary

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as PLOSARACETAM ChEMBL registry synonym — accepted as the source's own label CHEMBL5314929 ↗
Known as ABBV-552 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05771428 ↗
2

NCT06278766 ↗

NCT05686980 ↗

Known as SDI-118 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05212116 ↗
2

NCT05486195 ↗

NCT05199142 ↗

Modality Small molecule “SDI-118 is a small molecule” PMID 36733374 ↗ Jan 2023
1

CHEMBL5314929 ↗

Route Oral “SDI-118 capsule self-administered orally once daily (QD) for 17 days.” NCT05199142 ↗