Drugs / Ofirnoflast
last change May 2026 re-read 2 minutes ago

Ofirnoflast

also known as HT-6184

Small molecule

Developed for
myelodysplastic syndrome · obesity disorder · type 2 diabetes mellitus
Investigated by
Halia Therapeutics, Inc.

Trials 2 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT07172867 Jan 2026 obesity disorder, type 2 diabetes mellitus Halia Therapeutics, Inc. Withdrawn No outcome recorded
Phase 2 NCT07052006 Dec 2023 → Jan 2026 overdue myelodysplastic syndrome Halia Therapeutics, Inc. Active not recruiting No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05447546 Comparator Jun 2022 → Jul 2023 Halia Therapeutics, Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT06241742 Comparator Feb → Apr 2024 Halia Therapeutics, Inc. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Ofirnoflast Ofirnoflast (HT-6184) and Semaglutide in Obese or Overweight Participants With Type 2 Diabetes Mellitus (T2DM)” NCT07172867
Known as HT-6184 “Ofirnoflast (HT-6184) and Semaglutide in Obese or Overweight Participants With Type 2 Diabetes Mellitus (T2DM)” NCT07172867
3

NCT07052006

NCT06241742

NCT05447546

Modality Small molecule CHEMBL5750400
Route Oral “administered as single oral doses” NCT05447546