Drugs / RONOPTERIN
last change Jun 2020 re-read 3 minutes ago

RONOPTERIN

Small molecule

Developed for
traumatic brain injury
Investigated by
veriNOS operations GmbH · ICON plc

Trials 2

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT02012582 Nov 2009 → Jun 2012 traumatic brain injury veriNOS operations GmbH Completed No outcome recorded
Phase 31 trial
Phase 3 NCT02794168 Jun 2016 → Jun 2020 traumatic brain injury veriNOS operations GmbH Completed No outcome recorded
Comparator or background therapy1 trial
Phase 1 NCT02992236 Comparator Aug 2015 → May 2016 — veriNOS operations GmbH Completed No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as RONOPTERIN ChEMBL registry synonym — accepted as the source's own label CHEMBL1230245 ↗
Known as 4-amino-tetrahydrobiopterin “Safety and pharmacodynamics of 4-amino-tetrahydrobiopterin (VAS203)” PMID 24831445 ↗ Jul 2014
Known as Ronopterin, (6r)- ChEMBL registry synonym — accepted as the source's own label CHEMBL1230245 ↗
Known as Ronopterina ChEMBL registry synonym — accepted as the source's own label CHEMBL1230245 ↗
Known as Ronopterine ChEMBL registry synonym — accepted as the source's own label CHEMBL1230245 ↗
Known as VAS203 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02794168 ↗
2

NCT02012582 ↗

NCT02992236 ↗

Action Inhibit “Nitric Oxide Synthase inhibitor VAS203” NCT02012582 ↗
Modality Small molecule “the antipterin VAS203” PMID 24831445 ↗ Jul 2014
Route Intravenous “i.v. infusion” NCT02012582 ↗