Drugs / AMG 820
last change May 2019 re-read 2 minutes ago

AMG 820

Monoclonal antibody targets CSF1R via inhibition

Developed for
cancer · colorectal cancer · malignant pancreatic neoplasm · non-small cell lung carcinoma
Investigated by
AmMax Bio, Inc. · Merck Sharp & Dohme LLC

Trials 2 · a red edge is where a trial was stopped

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01444404 Mar 2008 → Feb 2014 cancer AmMax Bio, Inc. Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02713529 Apr 2016 → Jan 2019 colorectal cancer, malignant pancreatic neoplasm, non-small cell lung carcinoma AmMax Bio, Inc. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as AMG 820 “A Phase1b/2 Study Assessing Safety and Anti-tumor Activity of AMG 820 in Combination With Pembrolizumab in Select Advanced Solid Tumors” NCT02713529
2

NCT01444404

NCT02713529

Action Inhibit “c-fms antagonistic antibody” NCT01444404
Modality Monoclonal antibody “fully human IgG2 c-fms antagonistic antibody” NCT01444404
Target CSF1R “c-fms antagonistic antibody” NCT01444404