Drugs / eplivanserin
eplivanserin
also known as
SR46349 · EPLIVANSERIN FUMARATE · Eplivanserin hemifumarate · Eplivanserina · Eplivanserine · SR-46349B
Small molecule targets HTR2A via inhibition
Trials 7 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT00913614 | Jun → Dec 2009 | sleep disorder, initiating and maintaining sleep | Sanofi | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT00313885 | Apr 2004 → Jun 2005 | fibromyalgia | Sanofi | Completed | No outcome recorded |
| Phase 35 trials | ||||||
| Phase 3 | NCT00805350 | Dec 2008 → Jun 2009 | insomnia | Sanofi | Completed | No outcome recorded |
| Phase 3 | NCT00679900 | Apr 2008 → Mar 2009 | sleep disorder, initiating and maintaining sleep | Sanofi | Completed | No outcome recorded |
| Phase 3 | NCT00308503 | Feb 2006 → Aug 2007 | insomnia, sleep disorder, initiating and maintaining sleep | Sanofi | Completed | No outcome recorded |
| Phase 3 | NCT00253968 | Nov 2005 → Jan 2008 | insomnia, sleep disorder, initiating and maintaining sleep | Sanofi | Completed | No outcome recorded |
| Phase 3 | NCT00253903 | Nov 2005 → Nov 2007 | insomnia, sleep disorder, initiating and maintaining sleep | Sanofi | Completed | No outcome recorded |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | eplivanserin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00313885 ↗ |
| Known as | EPLIVANSERIN FUMARATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL257704 ↗ |
| Known as | Eplivanserin hemifumarate | ChEMBL registry synonym — accepted as the source's own label CHEMBL257704 ↗ |
| Known as | Eplivanserina | ChEMBL registry synonym — accepted as the source's own label CHEMBL257704 ↗ |
| Known as | Eplivanserine | ChEMBL registry synonym — accepted as the source's own label CHEMBL257704 ↗ |
| Known as | SR-46349B | ChEMBL registry synonym — accepted as the source's own label CHEMBL257704 ↗ |
| Known as | SR46349 | “Drug: eplivanserin (SR46349)” NCT00679900 ↗4“Drug: eplivanserin (SR46349)” NCT00308503 ↗ “eplivanserin (SR46349)” NCT00313885 ↗ “Eplivanserin (SR46349)” NCT00913614 ↗ “eplivanserin (SR46349)” NCT00253903 ↗ |
| Action | Inhibit | “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL257704 ↗ |
| Modality | Small molecule | — CHEMBL257704 ↗ |
| Route | Oral | “oral administration” NCT00253903 ↗ |
| Target | HTR2A | “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL257704 ↗ |