Drugs / INDENEBART
last change Jul 2025 re-read 3 minutes ago

INDENEBART

also known as MEDI1341 · TAK-341

Monoclonal antibody

Developed for
Parkinson disease · multiple system atrophy
Investigated by
AstraZeneca · Takeda · Catalent · Covance · MMS Holdings, Inc

Trials 3

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04449484 Aug 2020 → Jan 2022 Parkinson disease AstraZeneca Completed No outcome recorded
Phase 1 NCT03272165 Oct 2017 → Mar 2021 Parkinson disease AstraZeneca Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT05526391 Nov 2022 → Jul 2025 multiple system atrophy Takeda Completed Missed primary

Press releases naming this drug 1 release

DateIssuerRelease
2017-08-29 AstraZeneca AstraZeneca and Takeda establish collaboration to develop and commercialise MEDI1341 for Parkinson’s disease astrazeneca.com ↗

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as INDENEBART ChEMBL registry synonym — accepted as the source's own label CHEMBL6068461 ↗
Known as MEDI1341 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04449484 ↗
1

NCT03272165 ↗

Known as TAK-341 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05526391 ↗
Modality Monoclonal antibody — CHEMBL6068461 ↗
Route Intravenous “single 60 minute intravenous infusion of MEDI1341 or placebo” NCT03272165 ↗