Drugs / DP001
last change Jul 2014 re-read 2 minutes ago

DP001

also known as 2MD

Small molecule targets PTH, VDR via inhibition / activation

Developed for
osteoporosis · secondary hyperparathyroidism · secondary hyperparathyroidism of renal origin
Investigated by
Deltanoid Pharmaceuticals

Trials 4 · a red edge is where a trial was stopped

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01969656 ? → Jun 2004 postmenopausal osteoporosis Deltanoid Pharmaceuticals Completed No outcome recorded
Phase 23 trials
Phase 2 NCT01922843 Sep 2013 → May 2014 end stage renal failure, secondary hyperparathyroidism Deltanoid Pharmaceuticals Completed No outcome recorded
Phase 2 NCT01653379 Aug 2012 → Jul 2014 secondary hyperparathyroidism of renal origin Deltanoid Pharmaceuticals Completed No outcome recorded
Phase 2 NCT00715676 Mar 2007 → Dec 2008 osteoporosis Deltanoid Pharmaceuticals Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as DP001 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00715676
2

NCT01653379

NCT01922843

Known as 2MD ClinicalTrials.gov intervention name — accepted as the source's own label NCT01969656
Action Activate “Vitamin D receptor agonist” CHEMBL605525
Action Inhibit “suppress PTH synthesis” NCT01653379
Modality Small molecule “DP001 is a vitamin D analog that has been shown to stimulate bone formation in pre-clinical studies.” NCT00715676
Route Oral oral, once daily” NCT00715676
Target PTH “suppress PTH synthesis” NCT01653379
Target VDR “Vitamin D receptor agonist” CHEMBL605525