Drugs / ZF874
last change Sep 2022 re-read 3 minutes ago

ZF874

Small molecule

Developed for
alpha 1-antitrypsin deficiency

Trials 0

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Comparator or background therapy1 trial
Phase 1 NCT04443192 Comparator Aug 2020 → Sep 2022 alpha 1-antitrypsin deficiency Z Factor Limited Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as ZF874 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04443192 ↗
Action Restore “specifically designed to rescue the folding of the Z variant of alpha-1-antitrypsin (A1AT)” NCT04443192 ↗
Modality Small molecule “ZF874 is a novel chemical chaperone” NCT04443192 ↗
Route Oral “Single oral dose of ZF874 by mouth in the fasted state” NCT04443192 ↗