Drugs / Surzebiclimab
last change Jul 2026 re-read 2 minutes ago

Surzebiclimab

also known as BGB-A425

Monoclonal antibody

Developed for
head and neck squamous cell carcinoma · cancer
Investigated by
BeiGene · BeOne Medicines

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT03744468 Nov 2018 → Feb 2025 head and neck squamous cell carcinoma BeiGene Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05909904 Aug 2023 → Jun 2025 overdue head and neck squamous cell carcinoma BeiGene Active not recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT04164199 Dec 2019 → May 2026 cancer BeOne Medicines Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Surzebiclimab ClinicalTrials.gov intervention name — accepted as the source's own label NCT03744468
1

NCT04164199

Known as BGB-A425 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05909904
Action Inhibit “surzebiclimab (anti TIM-3)” NCT03744468
Modality Monoclonal antibody CHEMBL4594464
Route Intravenous “surzebiclimab 2 mg intravenous (IV) infusion on day 1 of each cycle” NCT03744468