Drugs / Ledaborbactam etzadroxil
Ledaborbactam etzadroxil
Trials 6 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT06733675 | Jan 2025 → Dec 2026 expected | — | Basilea Pharmaceutica | Recruiting | No outcome recorded |
| Phase 1 | NCT06665555 | Nov 2024 → Mar 2025 | — | Basilea Pharmaceutica | Completed | No outcome recorded |
| Phase 1 | NCT05488678 | Oct 2022 → Nov 2023 | — | Basilea Pharmaceutica | Completed | No outcome recorded |
| Phase 1 | NCT05527834 | Sep 2022 → Feb 2023 | — | Basilea Pharmaceutica | Completed | No outcome recorded |
| Phase 1 | NCT04877379 | Jun → Nov 2021 | — | Basilea Pharmaceutica | Completed | No outcome recorded |
| Phase 1 | NCT04243863 | Jan 2020 → Apr 2021 | — | Basilea Pharmaceutica | Completed | No outcome recorded |
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Ledaborbactam etzadroxil | “Ledaborbactam etzadroxil (LED-E), a novel oral prodrug that converts to the active β-lactamase inhibitor (BLI) ledaborbactam (LED), is being developed in combination with...” PMID 40762486 ↗ Aug 2025 |
| Known as | LED-E | “Ledaborbactam etzadroxil (LED-E), a novel oral prodrug that converts to the active β-lactamase inhibitor (BLI) ledaborbactam (LED), is being developed in combination with...” PMID 40762486 ↗ Aug 20251“Ledaborbactam etzadroxil (LED-E) is an oral prodrug of ledaborbactam, a broad-spectrum β-lactamase inhibitor.” PMID 42008649 ↗ Apr 2026 |
| Known as | VNRX-5236 ETZADROXIL | ChEMBL registry synonym — accepted as the source's own label CHEMBL4594425 ↗ |
| Known as | VNRX-7145 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05488678 ↗ |
| Action | Inhibit | “active β-lactamase inhibitor (BLI)” PMID 40762486 ↗ Aug 2025 |
| Modality | Small molecule | — CHEMBL4594425 ↗ |
| Route | Oral | “Oral dosing” NCT04243863 ↗ |