Drugs / GSK5764227
last change Jul 2026 re-read 3 minutes ago

GSK5764227

Developed for
neoplasm · digestive system neoplasm · head and neck squamous cell carcinoma
Investigated by
GlaxoSmithKline · University Health Network, Toronto

Trials 4

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT07277270 Dec 2025 → Jul 2026 overdue neoplasm GlaxoSmithKline Recruiting No outcome recorded
Phase 1 NCT05277051 Mar 2022 → Aug 2027 expected neoplasm GlaxoSmithKline Active not recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT06885034 Jun 2025 → Jan 2028 expected digestive system neoplasm GlaxoSmithKline Recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT07408063 Apr 2026 → Jun 2030 expected head and neck squamous cell carcinoma University Health Network, Toronto Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as GSK5764227 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07408063 ↗
3

NCT06885034 ↗

NCT05277051 ↗

NCT07277270 ↗

Action Deplete “delivers a toxin directly to cancer cells to destroy them while sparing healthy cells” NCT07277270 ↗
Route Intravenous “All participants will receive GSK5764227 monotherapy at a starting dose of 8 mg/kg Intravenously every 3 weeks (IV Q3W) in a 21-day treatment cycle.” NCT07408063 ↗