Drugs / Pozanicline
last change Jan 2014 re-read 2 minutes ago

Pozanicline

Small molecule

Developed for
attention deficit-hyperactivity disorder · Alzheimer disease · nicotine dependence
Investigated by
AbbVie · Abbott

Trials 10 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00809510 Jan → Jun 2009 Alzheimer disease Abbott Terminated No outcome recorded
Phase 2 NCT00686933 May → Oct 2008 attention deficit-hyperactivity disorder AbbVie Completed No outcome recorded
Phase 2 NCT00640419 Mar → Jul 2008 attention deficit-hyperactivity disorder AbbVie Completed No outcome recorded
Phase 2 NCT00640185 Mar → Aug 2008 attention deficit-hyperactivity disorder AbbVie Completed No outcome recorded
Phase 2 NCT00554385 Nov 2007 → Aug 2008 attention deficit-hyperactivity disorder Abbott Terminated No outcome recorded
Phase 2 NCT00555204 Nov 2007 → Jun 2009 Alzheimer disease Abbott Terminated No outcome recorded
Phase 2 NCT00528697 Sep 2007 → Apr 2008 attention deficit-hyperactivity disorder AbbVie Completed No outcome recorded
Phase 2 NCT00443391 Feb 2007 → Oct 2008 attention deficit-hyperactivity disorder AbbVie Completed No outcome recorded
Phase 2 NCT00391729 Oct 2006 → Jun 2007 attention deficit-hyperactivity disorder Abbott Completed No outcome recorded
Phase 2 NCT00069849 Jul 2003 → ? Alzheimer disease Abbott Terminated No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01756053 Comparator Mar 2013 → Jan 2014 nicotine dependence University of Pennsylvania Terminated No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 13 sources stand behind the page.

FieldValueCited text
Known as Pozanicline PozaniclineNCT01756053
Known as A-87089.0 ChEMBL registry synonym — accepted as the source's own label CHEMBL127071
Known as A-87089.74 ChEMBL registry synonym — accepted as the source's own label CHEMBL127071
Known as ABT-089 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00640419
10

NCT00555204

NCT00069849

NCT00640185

NCT00686933

NCT00391729

NCT01756053

NCT00443391

NCT00809510

NCT00528697

NCT00554385

Known as Pozaniclina ChEMBL registry synonym — accepted as the source's own label CHEMBL127071
Known as POZANICLINE TARTRATE ChEMBL registry synonym — accepted as the source's own label CHEMBL127071
Action Activate “the α(4)β(2) NNR partial agonist ABT-089 versus placebo in adults with ADHD” PMID 21748252 Jul 2011
Modality Small molecule CHEMBL127071
Route Oral “Subjects will take up to two 40 mg tablets once daily for 8 weeks.” NCT00640185