Drugs / AMV564
last change Dec 2021 re-read 3 minutes ago

AMV564

also known as CNTO 3953 TANDAB · CNTO-3953 · T-652 · Vixtimotamab

Protein / enzyme biologic targets CD33

Developed for
acute myeloid leukemia · myelodysplastic syndrome
Investigated by
Amphivena Therapeutics, Inc.

Trials 3

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04128423 Oct 2019 → Dec 2021 — Amphivena Therapeutics, Inc. Unknown No outcome recorded
Phase 1 NCT03516591 Jun 2018 → Jul 2020 myelodysplastic syndrome Amphivena Therapeutics, Inc. Completed No outcome recorded
Phase 1 NCT03144245 Mar 2017 → Jul 2020 acute myeloid leukemia Amphivena Therapeutics, Inc. Completed No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as AMV564 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03144245 ↗
2

NCT04128423 ↗

NCT03516591 ↗

Known as CNTO 3953 TANDAB ChEMBL registry synonym — accepted as the source's own label CHEMBL4297552 ↗
Known as CNTO-3953 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297552 ↗
Known as T-652 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297552 ↗
Known as Vixtimotamab ChEMBL registry synonym — accepted as the source's own label CHEMBL4297552 ↗
Modality Protein / enzyme biologic “a CD33 x CD3 Tandem Diabody” NCT03144245 ↗
Route Intravenous “AMV564 for administration via continuous intravenous daily infusion or subcutaneous dosing” NCT03144245 ↗
Route Subcutaneous “AMV564 for administration via continuous intravenous daily infusion or subcutaneous dosing” NCT03144245 ↗
Target CD33 “a CD33 x CD3 Tandem Diabody” NCT03144245 ↗