Drugs / EVETIFATOR
last change Oct 2024 re-read 2 minutes ago

EVETIFATOR

also known as DNL343

Small molecule

Developed for
amyotrophic lateral sclerosis
Investigated by
Denali Therapeutics Inc. · Merit E. Cudkowicz, MD · Massachusetts General Hospital

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT06281158 Mar → Apr 2024 Denali Therapeutics Inc. Completed No outcome recorded
Phase 1 NCT05006352 Aug 2021 → Dec 2022 amyotrophic lateral sclerosis Denali Therapeutics Inc. Completed No outcome recorded
Phase 1 NCT04581772 Dec 2020 → Jun 2021 Denali Therapeutics Inc. Completed No outcome recorded
Phase 1 NCT04268784 Feb 2020 → Aug 2021 Denali Therapeutics Inc. Completed No outcome recorded
Phase 2/32 trials
Phase 2/3 NCT05842941 May 2023 → Oct 2024 amyotrophic lateral sclerosis Merit E. Cudkowicz, MD Completed No outcome recorded
Phase 2/3 NCT04297683 Jun 2020 → Jul 2027 expected amyotrophic lateral sclerosis Merit E. Cudkowicz, MD Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as EVETIFATOR ChEMBL registry synonym — accepted as the source's own label CHEMBL5569312
Known as DNL343 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04297683
5

NCT04581772

NCT06281158

NCT05006352

NCT05842941

NCT04268784

Modality Small molecule CHEMBL5569312
Route Oral “Single and repeating oral dose(s)” NCT04268784