Drugs / Cinrebafusp alfa
last change Dec 2023 re-read 2 minutes ago

Cinrebafusp alfa

also known as PRS-343

Other / unclassified

Developed for
HER2 positive breast carcinoma · urinary bladder cancer · carcinoma
Investigated by
Pieris Pharmaceuticals GmbH

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03650348 Aug 2018 → Aug 2022 HER2 positive breast carcinoma, urinary bladder cancer Pieris Pharmaceuticals GmbH Completed No outcome recorded
Phase 1 NCT03330561 Sep 2017 → Dec 2023 HER2 positive breast carcinoma, urinary bladder cancer Pieris Pharmaceuticals GmbH Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05190445 Nov 2021 → Feb 2023 overdue carcinoma Pieris Pharmaceuticals GmbH Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Cinrebafusp alfa ClinicalTrials.gov intervention name — accepted as the source's own label NCT05190445
Known as PRS-343 “cinrebafusp alfa (PRS-343) in combination with ramucirumab and paclitaxel” NCT05190445
2

NCT03330561

NCT03650348

Action Activate “HER2 targeted CD137 agonist” NCT03330561
Modality Other / unclassified “HER2/4-1BB Bispecific” NCT03650348
Route Intravenous “administered by intravenous (IV) infusion” NCT03330561