Drugs / MVX-220
last change Oct 2025 re-read 3 minutes ago

MVX-220

targets UBE3A via restoration

Developed for
Angelman syndrome
Investigated by
MavriX Bio, LLC

Trials 1

202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT07181837 Oct 2025 → Mar 2028 expected Angelman syndrome MavriX Bio, LLC Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as MVX-220 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07181837 ↗
Action Restore “MVX-220 is an investigational gene replacement therapy intended to provide a functional copy of the UBE3A gene” NCT07181837 ↗
Route Other “single dose intra cisterna magna injection” NCT07181837 ↗
Target UBE3A “functional copy of the UBE3A gene” NCT07181837 ↗