Drugs / ERTEBEREL
last change Sep 2024 re-read 2 minutes ago

ERTEBEREL

also known as LY500307 · Serba-1

Small molecule targets ESR2 via activation

Developed for
benign prostatic hyperplasia · schizophrenia
Investigated by
Eli Lilly and Company · Indiana University · National Institute of Mental Health (NIMH)

Trials 3 · a red edge is where a trial was stopped

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT03689543 May 2019 → Sep 2024 National Institute of Mental Health (NIMH) Completed No outcome recorded
Phase 2 NCT01874756 Jun 2013 → Dec 2017 schizophrenia Indiana University Terminated No outcome recorded
Phase 2 NCT01097707 Apr 2010 → Oct 2011 benign prostatic hyperplasia Eli Lilly and Company Terminated No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as ERTEBEREL ChEMBL registry synonym — accepted as the source's own label CHEMBL278703
Known as LY500307 “Lilly Compound LY500307, a selective estrogen receptor (ER) beta agonist” NCT03689543
2

NCT01874756

NCT01097707

Known as Serba-1 ChEMBL registry synonym — accepted as the source's own label CHEMBL278703
Action Activate “Estrogen receptor beta agonist” CHEMBL278703
1

“selective ERβ agonist LY500307” NCT01874756

Modality Small molecule CHEMBL278703
Route Oral “Administered orally, daily for 24 weeks” NCT01097707
Target ESR2 “Estrogen receptor beta agonist” CHEMBL278703