Drugs / SHR2285
last change Mar 2023 re-read 2 minutes ago

SHR2285

Small molecule

Developed for
thrombotic disease
Investigated by
Jiangsu HengRui Medicine Co., Ltd. · Atridia Pty Ltd. · Shanghai Hengrui Pharmaceutical Co., Ltd.

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT04945616 Jul → Oct 2021 thrombotic disease Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 1 NCT04829305 May → Sep 2021 Atridia Pty Ltd. Completed No outcome recorded
Phase 1 NCT04472819 Aug 2020 → May 2021 thrombotic disease Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 1 NCT04229433 Aug → Nov 2020 thrombotic disease Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 1 NCT03769831 Feb → Jul 2019 thrombotic disease Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05203705 Mar 2022 → Mar 2023 Shanghai Hengrui Pharmaceutical Co., Ltd. Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as SHR2285 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04472819
5

NCT04829305

NCT03769831

NCT04945616

NCT05203705

NCT04229433

Action Inhibit “the inhibition of FXI activity was synchronized with prolonged activated partial thromboplastin time after SHR2285 administration” PMID 35222036 Feb 2022
Modality Small molecule “Small-Molecule Factor XIa Inhibitor” PMID 35222036 Feb 2022
Route Oral “Subjects assigned to the SHR2285 group received a single oral dose of SHR2285 at 50 mg” PMID 35222036 Feb 2022