Drugs / SHR2285
last change Mar 2023 re-read 9 days ago

SHR2285

Small molecule

Developed for
thrombotic disease
Investigated by
Jiangsu HengRui Medicine Co., Ltd. · Atridia Pty Ltd. · Shanghai Hengrui Pharmaceutical Co., Ltd.

Trials 6

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT04945616 Jul → Oct 2021 thrombotic disease Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 1 NCT04829305 May → Sep 2021 — Atridia Pty Ltd. Completed No outcome recorded
Phase 1 NCT04472819 Aug 2020 → May 2021 thrombotic disease Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 1 NCT04229433 Aug → Nov 2020 thrombotic disease Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 1 NCT03769831 Feb → Jul 2019 thrombotic disease Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05203705 Mar 2022 → Mar 2023 — Shanghai Hengrui Pharmaceutical Co., Ltd. Terminated No outcome recorded Stop: Business

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as SHR2285 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05203705 ↗
5

NCT04472819 ↗

NCT04229433 ↗

NCT04829305 ↗

NCT04945616 ↗

NCT03769831 ↗

Action Inhibit “the inhibition of FXI activity was synchronized with prolonged activated partial thromboplastin time after SHR2285 administration” PMID 35222036 ↗ Feb 2022
Modality Small molecule “Small-Molecule Factor XIa Inhibitor” PMID 35222036 ↗ Feb 2022
Route Oral “Subjects assigned to the SHR2285 group received a single oral dose of SHR2285 at 50 mg” PMID 35222036 ↗ Feb 2022