Drugs / Sinomenine
Sinomenine
Trials 1 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 3 | NCT05764304 | Feb 2023 → Feb 2025 | osteoarthritis, knee | Shanghai 6th People's Hospital | Unknown | No outcome recorded |
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Sinomenine | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05764304 ↗ |
| Known as | Cucoline | ChEMBL registry synonym — accepted as the source's own label CHEMBL248095 ↗ |
| Known as | Kukoline | ChEMBL registry synonym — accepted as the source's own label CHEMBL248095 ↗ |
| Known as | Sinomenin | ChEMBL registry synonym — accepted as the source's own label CHEMBL248095 ↗ |
| Action | Inhibit | “Sinomenine at a concentration of 20 μg/mL mitigated inflammation by suppressing the expression of tumor necrosis factor alpha and interleukin 6” PMID 41560786 ↗ Dec 2025 |
| Modality | Small molecule | “sinomenine, a natural alkaloid with immunomodulatory properties” PMID 41560786 ↗ Dec 2025 |
| Route | Other | “intra-articular sinomenine hydrochloride” PMID 41560786 ↗ Dec 2025 |