Drugs / Akynzeo
last change Dec 2023 re-read 2 minutes ago

Akynzeo

Developed for
chemotherapy-induced toxicity
Investigated by
Christina Ruhlmann · Chugai Pharma UK Limited · Helsinn Healthcare SA · Imperial College Healthcare NHS Trust

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved EU (EMA) Akynzeo 2015-05-27 europa.eu
Approved US (FDA) AKYNZEO 2014-10-10 fda.gov

Trials 2 · a red edge is where a trial was stopped

today
US approved 2014
EU approved 2015
NCT04362449 · Ph 2 NCT03668639 · Ph 2/3
2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT04362449 Jan 2019 → Feb 2023 gallbladder cancer Imperial College Healthcare NHS Trust Unknown No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT03668639 Sep 2018 → Mar 2023 cervical cancer, chemotherapy-induced toxicity Christina Ruhlmann Unknown No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT06065722 Comparator Sep → Dec 2023 chemotherapy-induced toxicity Simon Williamson Clinic Unknown No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Akynzeo ClinicalTrials.gov intervention name — accepted as the source's own label NCT03668639
2

NCT04362449

NCT06065722

Action Inhibit “Akynzeo contains a combination of the neurokinin-1 receptor antagonist netupitant and the serotonin receptor antagonist palonosetron.” NCT03668639
Route Oral “Akynzeo is administered as an oral drug” NCT04362449