Drugs / MPT-0118
last change Mar 2023 re-read 3 minutes ago

MPT-0118

also known as (S)-mepazine succinate

targets MALT1 via inhibition

Developed for
metastatic malignant neoplasm · refractory malignant neoplasm
Investigated by
Monopteros Therapeutics Inc.

Trials 1

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04859777 Apr 2021 → Mar 2023 metastatic malignant neoplasm, refractory malignant neoplasm Monopteros Therapeutics Inc. Unknown No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as MPT-0118 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04859777 ↗
Known as (S)-mepazine succinate “This translational study supports ongoing clinical investigations (ClinicalTrials.gov Identifier: NCT04859777) of MPT-0118, (S)-mepazine succinate, in patients with advanced or...” PMID 37214210 ↗ Mar 2023
Action Inhibit “MPT-0118 is an inhibitor of MALT1 protease” NCT04859777 ↗
Route Oral “MPT-0118 will be administered orally twice daily (BID).” NCT04859777 ↗
Target MALT1 “MPT-0118 is an inhibitor of MALT1 protease” NCT04859777 ↗