Drugs / Humanized CD19 CAR-T cells
last change Aug 2026 re-read 3 minutes ago

Humanized CD19 CAR-T cells

also known as hCART19

Cell therapy targets CD19

Developed for
B-cell acute lymphoblastic leukemia
Investigated by
Yake Biotechnology Ltd. · Zhejiang University

Trials 1

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 0 NCT04532268 Aug 2020 → Aug 2023 overdue B-cell acute lymphoblastic leukemia Zhejiang University Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Humanized CD19 CAR-T cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT04532268 ↗
Known as hCART19 “We performed a clinical trial to determine the safety and efficacy of autologous and allogeneic humanized CD19-targeted CAR-T cell (hCART19) for R/R B-ALL.” PMID 36808074 ↗ Feb 2023
Modality Cell therapy “Chimeric antigen receptor T (CAR-T) cell therapy is highly effective in inducing complete remission in haematological malignancies.” PMID 37192741 ↗ May 2023
Route Intravenous “Each subject receive humanized CD19 CAR-T cells by intravenous infusion” NCT04532268 ↗
Target CD19 “We performed a clinical trial to determine the safety and efficacy of autologous and allogeneic humanized CD19-targeted CAR-T cell (hCART19) for R/R B-ALL.” PMID 36808074 ↗ Feb 2023