Drugs / NX-13
last change May 2025 re-read 3 minutes ago

NX-13

targets NLRX1 via activation

Developed for
ulcerative colitis
Investigated by
Landos Biopharma Inc. · AbbVie

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04862741 May 2021 → Jun 2022 ulcerative colitis Landos Biopharma Inc. Completed No outcome recorded
Phase 1 NCT04458805 Jul → Oct 2020 ulcerative colitis Landos Biopharma Inc. Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT05785715 Apr 2023 → May 2025 ulcerative colitis AbbVie Terminated Missed primary Stop: Business

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as NX-13 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04458805 ↗
2

NCT04862741 ↗

NCT05785715 ↗

Action Activate “NX-13 activation of NLRX1 reduces intracellular reactive oxygen species and decreases inflammation in animal models of colitis.” PMID 37952114 ↗ May 2024
Route Oral “single oral dose” NCT04458805 ↗
Target NLRX1 “NX-13 activation of NLRX1 reduces intracellular reactive oxygen species and decreases inflammation in animal models of colitis.” PMID 37952114 ↗ May 2024