Drugs / LY4100511
last change Sep 2025 re-read 9 days ago

LY4100511

also known as DC-853 · DICE-853
Developed for
psoriasis
Investigated by
DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company · Eli Lilly and Company

Trials 7

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 16 trials
Phase 1 NCT06916143 Apr 2025 — Eli Lilly and Company Terminated No outcome recorded
Phase 1 NCT06627088 Aug → Dec 2024 — DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT06503679 Jul → Dec 2024 — DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT06345794 Apr → Jun 2024 — DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT06311656 Mar → Oct 2024 — DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT06937411 Feb → Oct 2023 — Eli Lilly and Company Completed No outcome recorded
Phase 21 trial
Phase 2 NCT06602219 Oct 2024 → Jul 2025 psoriasis DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as LY4100511 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06602219 ↗
6

NCT06916143 ↗

NCT06345794 ↗

NCT06311656 ↗

NCT06937411 ↗

NCT06627088 ↗

NCT06503679 ↗

Known as DC-853 “A Study to Evaluate Safety, Tolerability of LY4100511 (DC-853) in Healthy Asian and Non-Asian Participants” NCT06311656 ↗
3

“LY4100511 (DC-853) administered orally alone then LY4100511 (DC-853) administered orally with Rabeprazole.” NCT06916143 ↗

“LY4100511 (DC-853) Dose 1” NCT06503679 ↗

“LY4100511 (DC-853)” NCT06627088 ↗

Known as DICE-853 “The main purpose of this study is to assess the effect of multiple doses of itraconazole, fluconazole, and carbamazepine on single dose pharmacokinetic of LY4100511 (DICE-853)...” NCT06345794 ↗
Route Oral “administered orally” NCT06311656 ↗