Drugs / LUCORAFUSP ALFA
last change Jun 2026 re-read 2 minutes ago

LUCORAFUSP ALFA

also known as AK130

Protein / enzyme biologic

Developed for
biliary tract cancer · cancer · hepatocellular carcinoma · malignant pancreatic neoplasm
Investigated by
Akeso

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05653284 Feb → Dec 2023 cancer Akeso Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT06938321 Apr 2025 → May 2027 expected biliary tract cancer Akeso Recruiting No outcome recorded
Phase 1/2 NCT06530251 Sep 2024 → Jun 2026 overdue hepatocellular carcinoma Akeso Recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT07114315 Sep 2025 → Aug 2027 expected malignant pancreatic neoplasm Akeso Recruiting No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2024-01-15 Akeso 康方PD-1/VEGF双抗依沃西联合卡度尼利/AK130/AK127治疗肝细胞癌Ⅰb/Ⅱ期临床研究获批 akesobio.com

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as LUCORAFUSP ALFA ChEMBL registry synonym — accepted as the source's own label CHEMBL6068134
Known as AK130 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07114315
3

NCT05653284

NCT06530251

NCT06938321

Modality Protein / enzyme biologic “AK130 (TIGIT/TGF-β bifunctional fusion protein)” NCT05653284
Route Intravenous “IV infusion, specified dose on specified days.” NCT05653284