Drugs / carbon monoxide
carbon monoxide
Trials 12
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 14 trials | ||||||
| Phase 1 | NCT04870125 | Dec 2023 → Oct 2024 | acute respiratory distress syndrome, infectious disease with sepsis | Brigham and Women's Hospital | Terminated | No outcome recorded Stop: Enrollment |
| Phase 1 | NCT03067701 | Jun 2017 → Dec 2018 | — | Cedars-Sinai Medical Center | Completed | No outcome recorded |
| Phase 1 | NCT01050933 | Sep 2010 → Jun 2011 | — | Queen's University | Terminated | No outcome recorded |
| Phase 1 | NCT00094406 | Oct 2004 → Mar 2010 | adult acute respiratory distress syndrome | National Institutes of Health Clinical Center (CC) | Completed | No outcome recorded |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT01727167 | Feb 2014 → Jan 2016 | heart disorder | John J Freiberger | Terminated | No outcome recorded Stop: Enrollment |
| Phase 1/2 | NCT01523548 | Jul 2012 → Dec 2018 | pulmonary arterial hypertension | University of Illinois at Chicago | Withdrawn | No outcome recorded Stop: Business |
| Phase 25 trials · 1 missed | ||||||
| Phase 2 | NCT07005180 | Jun → Dec 2026 expected | Parkinson disease | Hillhurst Biopharmaceuticals, Inc. | Recruiting | No outcome recorded |
| Phase 2 | NCT03799874 | Sep 2019 → Apr 2021 | acute respiratory distress syndrome | Brigham and Women's Hospital | Completed | No outcome recorded |
| Phase 2 | NCT01214187 | Jul 2011 → Oct 2014 | idiopathic pulmonary fibrosis | Brigham and Women's Hospital | Completed | Missed primary |
| Phase 2 | NCT00531856 | Aug 2007 → Aug 2011 | — | Mallinckrodt | Withdrawn | No outcome recorded |
| Phase 2 | NCT00122694 | Jan 2005 → Mar 2006 | chronic obstructive pulmonary disease | Groningen Research Institute for Asthma and COPD | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT06739538 | Mar → Sep 2024 overdue | cerebral palsy | Superior University | Active not recruiting | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 14 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Carbon Monoxide | “This study will test if inhalation of Carbon Monoxide (CO) will increase the numbers of mitochondria in heart muscle.” NCT01727167 ↗11“such as nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H₂S), are small gaseous signaling molecules” NCT06739538 ↗ “HBI-002, an Oral Low-dose Carbon Monoxide (CO) Liquid Drug Product” NCT07005180 ↗ |
| Known as | Carbon monoxide, c-11 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1231840 ↗ |
| Known as | Carbon oxide (co) | ChEMBL registry synonym — accepted as the source's own label CHEMBL1231840 ↗ |
| Known as | Carboneum oxygenisatum | ChEMBL registry synonym — accepted as the source's own label CHEMBL1231840 ↗ |
| Known as | CO | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01727167 ↗ |
| Known as | HBI-002 | “HBI-002, an Oral Low-dose Carbon Monoxide (CO) Liquid Drug Product” NCT07005180 ↗ |
| Action | Inhibit | “low-dose CO blocks transcription of heme importers” PMID 35868533 ↗ Jul 2022 |
| Modality | Other / unclassified | “The gaseous molecule carbon monoxide (CO)” NCT00094406 ↗ |
| Route | Inhaled | “breathe CO or room air through a mask for 6 hours” NCT00094406 ↗ |