Drugs / tamuzimod
last change Dec 2025 re-read 2 minutes ago

tamuzimod

also known as VTX002 · OPL-002

Small molecule

Developed for
amyotrophic lateral sclerosis · ulcerative colitis
Investigated by
Oppilan Pharma Ltd · Celerion · Vector Y Therapeutics

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04451811 Sep 2020 → Feb 2021 Oppilan Pharma Ltd Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT07287397 Dec 2025 → Oct 2027 expected amyotrophic lateral sclerosis Vector Y Therapeutics Recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT05156125 Nov 2021 → Aug 2023 ulcerative colitis Oppilan Pharma Ltd Terminated No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as tamuzimod Tamuzimod (VTX002) is a selective sphingosine 1-phosphate receptor 1 modulator in development for ulcerative colitis.” PMID 39793589 Jan 2025
Known as OPL-002 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04451811
Known as VTX002 “Tamuzimod (VTX002) is a selective sphingosine 1-phosphate receptor 1 modulator in development for ulcerative colitis.” PMID 39793589 Jan 2025
2

“intracisternal administration of Vtx-002 in participants with Amyotrophic Lateral Sclerosis (ALS).” NCT07287397

NCT07287397

Modality Small molecule CHEMBL5314488
Route Oral oral OPL-002” NCT04451811