Drugs / Migaldendranib
last change Aug 2026 re-read 3 minutes ago

Migaldendranib

also known as D-4517.2 · MGB

Small molecule

Developed for
diabetic macular edema · wet macular degeneration
Investigated by
Ashvattha Therapeutics, Inc.

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT07370155 Jan → Aug 2026 overdue — Ashvattha Therapeutics, Inc. Recruiting No outcome recorded
Phase 1 NCT05105607 Jan → Aug 2022 diabetic macular edema, wet macular degeneration Ashvattha Therapeutics, Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05387837 Aug 2022 → May 2025 overdue diabetic macular edema, wet macular degeneration Ashvattha Therapeutics, Inc. Active not recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Migaldendranib “Migaldendranib (MGB)” NCT07370155 ↗
Known as D-4517.2 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05105607 ↗
1

NCT05387837 ↗

Known as MGB “Migaldendranib (MGB)” NCT07370155 ↗
Action Inhibit “Hydroxyl Dendrimer VEGFR Tyrosine Kinase Inhibitor” NCT05105607 ↗
Modality Small molecule — CHEMBL5314851 ↗
Route Subcutaneous “Subcutaneous (SC) injection” NCT05105607 ↗