Drugs / BNT166a
last change Jun 2026 re-read 3 minutes ago

BNT166a

Messenger RNA (mRNA)

Developed for
monkeypox · human infection by orthopoxvirus · smallpox
Investigated by
BioNTech SE · Coalition for Epidemic Preparedness Innovations

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT05988203 Sep 2023 → Aug 2025 monkeypox BioNTech SE Completed No outcome recorded
Phase 21 trial
Phase 2 NCT07379580 Feb 2026 → Jun 2027 expected human infection by orthopoxvirus, monkeypox, smallpox BioNTech SE Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as BNT166a ClinicalTrials.gov intervention name — accepted as the source's own label NCT07379580 ↗
1

NCT05988203 ↗

Modality Messenger RNA (mRNA) “The quadrivalent mRNA vaccine candidate BNT166a encoding MPXV antigens A35, B6, M1, and H3 was selected for clinical development” PMID 42235570 ↗ Jun 2026
Route Intramuscular “administered as intramuscular injection” NCT05988203 ↗