Drugs / CERE-110
last change Jul 2018 re-read 3 minutes ago

CERE-110

Gene therapy (AAV / viral vector) targets NGF

Developed for
Alzheimer disease
Investigated by
Sangamo Therapeutics · Alzheimer's Disease Cooperative Study (ADCS) · Ceregene

Trials 2

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00087789 Jun 2004 → May 2010 Alzheimer disease Sangamo Therapeutics Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT00876863 Nov 2008 → Aug 2015 Alzheimer disease Sangamo Therapeutics Completed Missed primary

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as CERE-110 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00087789 ↗
1

NCT00876863 ↗

Modality Gene therapy (AAV / viral vector) “Adeno-Associated Virus Delivery” NCT00087789 ↗
Route Other “intracerebral injections” PMID 29582053 ↗ Jul 2018
Target NGF “CERE-110 uses a virus to transfer a gene that makes Nerve Growth Factor (NGF), a protein that may make nerve cells in the brain healthier and protect them from dying.” NCT00876863 ↗