Drugs / JYP0015
last change Mar 2026 re-read 3 minutes ago

JYP0015

targets HRAS, KRAS, NRAS via inhibition

Developed for
colorectal cancer · non-small cell lung carcinoma · pancreatic ductal adenocarcinoma
Investigated by
Guangzhou JOYO Pharma Co., Ltd

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT06895031 Mar 2025 → Mar 2026 overdue colorectal cancer, non-small cell lung carcinoma, pancreatic ductal adenocarcinoma Guangzhou JOYO Pharma Co., Ltd Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as JYP0015 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06895031 ↗
Action Inhibit “JYP0015 is a potent, orally bioavailable pan-RAS inhibitor” NCT06895031 ↗
Route Oral “The drug will be administered orally” NCT06895031 ↗
Target HRAS “JYP0015 is an orally bioavailable pan-RAS inhibitor designed to target the active (ON) form of wild-type and mutant RAS across KRAS, NRAS, and HRAS isoforms.” NCT06895031 ↗
Target KRAS “JYP0015 is an orally bioavailable pan-RAS inhibitor designed to target the active (ON) form of wild-type and mutant RAS across KRAS, NRAS, and HRAS isoforms.” NCT06895031 ↗
Target NRAS “JYP0015 is an orally bioavailable pan-RAS inhibitor designed to target the active (ON) form of wild-type and mutant RAS across KRAS, NRAS, and HRAS isoforms.” NCT06895031 ↗