Drugs / AMG 317
last change Jan 2010 re-read 3 minutes ago

AMG 317

Monoclonal antibody targets IL4R via inhibition

Developed for
asthma
Investigated by
Amgen

Trials 1

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00436670 Mar 2007 → Sep 2008 asthma Amgen Completed Missed primary

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as AMG 317 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00436670 ↗
Action Inhibit “that blocks both IL-4 and IL-13 pathways” PMID 20056900 ↗ Jan 2010
Modality Monoclonal antibody “AMG 317 is a fully human monoclonal antibody to IL-4Ralpha” PMID 20056900 ↗ Jan 2010
Route Subcutaneous “patients received weekly subcutaneous injections of placebo or AMG 317 (75-300 mg) for 12 weeks” PMID 20056900 ↗ Jan 2010
Target IL4R “AMG 317 is a fully human monoclonal antibody to IL-4Ralpha” PMID 20056900 ↗ Jan 2010