Drugs / Bifeprunox

Trials 19 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00581451 Oct 2007 → Dec 2008 Wyeth is now a wholly owned subsidiary of Pfizer Completed No outcome recorded
Phase 24 trials
Phase 2 NCT00139919 Jan 2006 → Oct 2007 bipolar disorder, schizoaffective disorder, schizophrenia Solvay Pharmaceuticals Completed No outcome recorded
Phase 2 NCT00139906 Aug 2005 → Oct 2006 schizoaffective disorder, schizophrenia Solvay Pharmaceuticals Completed No outcome recorded
Phase 2 NCT00141479 May 2005 → Nov 2006 schizoaffective disorder, schizophrenia Solvay Pharmaceuticals Completed No outcome recorded
Phase 2 NCT00141505 Feb 2005 → Dec 2006 bipolar I disorder Solvay Pharmaceuticals Completed No outcome recorded
Phase 314 trials
Phase 3 NCT00704509 Jun 2008 → Aug 2009 schizophrenia H. Lundbeck A/S Terminated No outcome recorded
Phase 3 NCT00658645 Mar 2008 → Aug 2009 schizophrenia H. Lundbeck A/S Terminated No outcome recorded
Phase 3 NCT00396214 Apr 2007 → Jan 2008 schizophrenia Solvay Pharmaceuticals Terminated No outcome recorded
Phase 3 NCT00366327 Jan 2007 → Mar 2008 schizophrenia Wyeth is now a wholly owned subsidiary of Pfizer Terminated No outcome recorded
Phase 3 NCT00366704 Nov 2006 → Mar 2008 schizophrenia Wyeth is now a wholly owned subsidiary of Pfizer Terminated No outcome recorded
Phase 3 NCT00366171 Nov 2006 → Oct 2007 schizophrenia Wyeth is now a wholly owned subsidiary of Pfizer Completed No outcome recorded
Phase 3 NCT00380224 Jul 2006 → Sep 2007 schizophrenia Wyeth is now a wholly owned subsidiary of Pfizer Completed No outcome recorded
Phase 3 NCT00861497 Jan 2006 → Jan 2008 schizophrenia H. Lundbeck A/S Terminated No outcome recorded
Phase 3 NCT00160147 Dec 2005 → Jan 2008 psychotic disorder Solvay Pharmaceuticals Terminated No outcome recorded
Phase 3 NCT00193687 Sep 2005 → Jan 2008 schizophrenia Solvay Pharmaceuticals Completed No outcome recorded

Evidence & citations 11 cited values

Every value below carries the sentence it was read from. 20 sources stand behind the page.

FieldValueCited text
Known as Bifeprunox ClinicalTrials.gov intervention name — accepted as the source's own label NCT00366327
18

NCT00139919

NCT00139906

NCT00160147

NCT00380224

NCT00581451

NCT00366171

NCT00193713

NCT00193687

NCT00141505

NCT00704509

NCT00366704

NCT00245973

NCT00861497

NCT00658645

NCT00134459

NCT00396214

NCT00230828

NCT00141479

Known as Befeprunox “A Multicenter, Randomized, Double-Blind, Parallel-Group Fixed-Dose Study of the Effect on Weight of Befeprunox Versus Olanzapine in the Treatment of Outpatients With Schizophrenia.” NCT00380224
Known as Bifeprunox mesilate ChEMBL registry synonym — accepted as the source's own label CHEMBL218166
Known as BIFEPRUNOX MESYLATE ChEMBL registry synonym — accepted as the source's own label CHEMBL218166
Known as Bifeprunox methanesulfonate ChEMBL registry synonym — accepted as the source's own label CHEMBL218166
Known as DU-127090 ChEMBL registry synonym — accepted as the source's own label CHEMBL218166
Action Activate “Serotonin 1a (5-HT1a) receptor partial agonist” CHEMBL218166
1

“Dopamine D2 receptor partial agonist” CHEMBL218166

Modality Small molecule CHEMBL218166
Route Oral “52 weeks of fixed oral doses of bifeprunox at 30 mg/day” NCT00396214
Target DRD2 “Dopamine D2 receptor partial agonist” CHEMBL218166
Target HTR1A “Serotonin 1a (5-HT1a) receptor partial agonist” CHEMBL218166