Drugs / AZD5153
last change Apr 2021 re-read 2 minutes ago

AZD5153

Small molecule targets BRD4 via inhibition

Developed for
acute myeloid leukemia · breast cancer · diffuse large B-cell lymphoma · lymphoma · malignant pancreatic neoplasm · ovarian cancer · prostate cancer
Investigated by
AstraZeneca · Acerta Pharma BV · Beat AML, LLC

Trials 3 · a red edge is where a trial was stopped

2017201820192020202120222023202420252026202720282029
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03527147 Jun 2018 → Mar 2021 diffuse large B-cell lymphoma Acerta Pharma BV Completed No outcome recorded
Phase 1 NCT03205176 Jun 2017 → Mar 2021 breast cancer, lymphoma, malignant pancreatic neoplasm, ovarian cancer +1 AstraZeneca Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03013998 Nov 2016 → Dec 2028 expected acute myeloid leukemia Beat AML, LLC Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as AZD5153 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03205176
2

NCT03013998

NCT03527147

Action Inhibit “BRD4 inhibitor” NCT03527147
Modality Small molecule CHEMBL4078100
Route Oral “20 mg, oral, once daily” NCT03013998
Target BRD4 BRD4 inhibitor” NCT03527147