Drugs / SB-007
last change Feb 2025 re-read 3 minutes ago

SB-007

Gene therapy (AAV / viral vector) targets ABCA4 via restoration

Developed for
Stargardt disease
Investigated by
Splice Bio

Trials 1

2025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT06942572 Feb 2025 → Oct 2028 expected Stargardt disease Splice Bio Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as SB-007 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06942572 ↗
Action Restore “for the full-length reconstitution of the ABCA4 protein inside the target cell” NCT06942572 ↗
Modality Gene therapy (AAV / viral vector) “dual AAV8 gene delivery” NCT06942572 ↗
Route Other “Subretinal Administration of SB-007” NCT06942572 ↗
Target ABCA4 “reconstitution of the full-length biologically active ABCA4 protein in target photoreceptor cells” NCT06942572 ↗