Drugs / KP-001
last change Feb 2026 re-read 2 minutes ago

KP-001

targets CYP1A2 via inhibition

Developed for
anaphylaxis · angioosteohypertrophic syndrome · CLOVES syndrome · lymphatic malformation · vascular malformation
Investigated by
Kaken Pharmaceutical · Kokua Pharma Inc. · Parexel

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT06963411 May → Jul 2025 anaphylaxis Kokua Pharma Inc. Completed No outcome recorded
Phase 1 NCT06821698 Feb → May 2025 Kaken Pharmaceutical Completed No outcome recorded
Phase 1 NCT06619054 Oct 2024 → May 2025 Kaken Pharmaceutical Completed No outcome recorded
Phase 1 NCT06649942 Oct 2024 → Mar 2025 Kaken Pharmaceutical Completed No outcome recorded
Phase 1 NCT06227832 Dec 2023 → Mar 2024 Kaken Pharmaceutical Completed No outcome recorded
Phase 31 trial
Phase 3 NCT07285005 Feb 2026 → Feb 2028 expected CLOVES syndrome, angioosteohypertrophic syndrome, lymphatic malformation, vascular malformation Kaken Pharmaceutical Not yet recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as KP001 “KP-001 therapeutic dose (T): KP-001 100 mg + placebo” NCT06649942
5

NCT06963411

NCT06821698

NCT07285005

NCT06227832

NCT06619054

Action Inhibit “KP-001 as an inducer and inhibitor of CYP1A2” NCT06821698
Route Oral Oral Doses of KP-001” NCT06227832
Target CYP1A2 “KP-001 as an inducer and inhibitor of CYP1A2NCT06821698