Drugs / MT-0169
last change Oct 2024 re-read 3 minutes ago

MT-0169

Protein / enzyme biologic targets CD38 via depletion

Developed for
leukemia · refractory plasma cell neoplasm
Investigated by
M.D. Anderson Cancer Center · Molecular Templates, Inc.

Trials 2

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06522373 Oct 2024 leukemia M.D. Anderson Cancer Center Withdrawn No outcome recorded
Phase 1 NCT04017130 Feb 2020 → Dec 2023 refractory plasma cell neoplasm Molecular Templates, Inc. Terminated No outcome recorded Stop: Enrollment

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as MT-0169 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06522373 ↗
1

NCT04017130 ↗

Action Deplete “It delivers a dose of a modified toxin that kills these cells.” NCT04017130 ↗
Modality Protein / enzyme biologic “MT-0169 (an Engineered toxin body (ETB)” NCT04017130 ↗
Route Intravenous “MT-0169 will be given as an intravenous (IV) infusion over 60 minutes” NCT04017130 ↗
Target CD38 “MT-0169 is an investigational drug that recognizes and binds to the CD38 receptor, which may be found on the surface of multiple myeloma cancer cells.” NCT04017130 ↗