Drugs / Levomethadyl acetate
Levomethadyl acetate
also known as
LAAM · Levacetilmetadol · Levacetylmethadol · Levacetylmethadol hydrochloride · Levo-alphacetylmethadol · Levoacetyl Methadol · Levomethadyl acetate hcl · LEVOMETHADYL ACETATE HYDROCHLORIDE · +2 more
Small molecule targets OPRM1 via activation
Trials 3
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials | ||||||
| Phase 2 | NCT00218127 | Nov 2001 → Jul 2005 | heroin dependence | National Institute on Drug Abuse (NIDA) | Completed | No outcome recorded |
| Phase 2 | NCT00344812 | Jan 1996 → Jun 1998 | opiate dependence | Johns Hopkins University | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT00000300 | Mar 1995 → ? | opiate dependence | University of California, Los Angeles | Completed | No outcome recorded |
Evidence & citations 14 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Levomethadyl acetate | “In a 17-week randomized study of 220 patients, we compared levomethadyl acetate (75 to 115 mg), buprenorphine (16 to 32 mg), and high-dose (60 to 100 mg) and low-dose (20 mg)...” PMID 11058673 ↗ Nov 2000 |
| Known as | LAAM | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00000300 ↗ |
| Known as | Levacetilmetadol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1514 ↗ |
| Known as | Levacetylmethadol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1514 ↗ |
| Known as | Levacetylmethadol hydrochloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL1514 ↗ |
| Known as | Levo-alphacetylmethadol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1514 ↗ |
| Known as | Levoacetyl Methadol | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00218127 ↗ |
| Known as | Levomethadyl acetate hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1514 ↗ |
| Known as | LEVOMETHADYL ACETATE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1514 ↗ |
| Known as | MK-790 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1514 ↗ |
| Known as | ORLAAM | “The purpose of this study is to determine the effectiveness of levoacetyl methadol (ORLAAM) in treating heroin dependent individuals.” NCT00218127 ↗ |
| Action | Activate | “Mu opioid receptor agonist” CHEMBL1514 ↗ |
| Modality | Small molecule | — CHEMBL1514 ↗ |
| Target | OPRM1 | “Mu opioid receptor agonist” CHEMBL1514 ↗ |