Drugs / BGT226
last change Mar 2010 re-read 3 minutes ago

BGT226

also known as NVP-BGT-226

Small molecule targets MTOR via inhibition

Developed for
breast cancer · cancer
Investigated by
Novartis Pharmaceuticals

Trials 2

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00742105 Nov 2008 → Dec 2009 cancer Novartis Pharmaceuticals Terminated No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT00600275 Dec 2007 → Mar 2010 Cowden disease, breast cancer Novartis Pharmaceuticals Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as BGT226 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00742105 ↗
1

NCT00600275 ↗

Known as NVP-BGT-226 ChEMBL registry synonym — accepted as the source's own label CHEMBL3218578 ↗
Action Inhibit “BGT226, an inhibitor of phosphatidylinositol 3'-kinase (PI3K)” NCT00600275 ↗
1

“Serine/threonine-protein kinase mTOR inhibitor” CHEMBL3218578 ↗

Modality Small molecule — CHEMBL3218578 ↗
Route Oral “BGT226, Administered Orally” NCT00600275 ↗
Target MTOR “Serine/threonine-protein kinase mTOR inhibitor” CHEMBL3218578 ↗