Drugs / AMDIZALISIB
last change Dec 2024 re-read 2 minutes ago

AMDIZALISIB

also known as HMPL-689

Small molecule

Developed for
lymphoma · follicular lymphoma · marginal zone lymphoma
Investigated by
Hutchison Medipharma Limited · Hutchmed

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT03786926 Aug 2019 → Jun 2024 lymphoma Hutchmed Terminated No outcome recorded
Phase 1 NCT03128164 Aug 2017 → Aug 2023 lymphoma Hutchison Medipharma Limited Completed No outcome recorded
Phase 1 NCT02631642 Mar → Oct 2016 Hutchison Medipharma Limited Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05713110 Feb 2023 → Dec 2024 lymphoma Hutchmed Completed No outcome recorded
Phase 2 NCT04849351 Apr 2021 → Feb 2024 follicular lymphoma, marginal zone lymphoma Hutchison Medipharma Limited Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as AMDIZALISIB ChEMBL registry synonym — accepted as the source's own label CHEMBL4438249
Known as HMPL-689 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03128164
4

NCT02631642

NCT03786926

NCT05713110

NCT04849351

Action Inhibit “selective PI3Kδ inhibitor” NCT02631642
Modality Small molecule “selective and potent small molecule inhibitor” NCT03786926
Route Oral “single oral doses of HMPL-689” NCT02631642