Drugs / Debio 1347
last change Jan 2022 re-read 2 minutes ago

Debio 1347

targets FGFR1, FGFR2, FGFR3 via inhibition

Developed for
cancer · breast cancer
Investigated by
Debiopharm International SA · Caris Life Sciences · Memorial Sloan Kettering Cancer Center · Optimal Research (Just In Time sites)

Trials 3 · a red edge is where a trial was stopped

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01948297 Aug 2013 → Jun 2020 cancer Debiopharm International SA Terminated No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03344536 Nov 2017 → Aug 2021 breast cancer Memorial Sloan Kettering Cancer Center Completed No outcome recorded
Phase 21 trial
Phase 2 NCT03834220 Mar 2019 → Dec 2020 cancer Debiopharm International SA Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Debio 1347 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03834220
2

NCT03344536

NCT01948297

Action Inhibit “Oral Selective Pan-FGFR Inhibitor Debio 1347” NCT03834220
Route Oral “Debio1347 orally administered daily” NCT01948297
Target FGFR1 “A Phase II Basket Study of the Oral Selective Pan-FGFR Inhibitor Debio 1347 in Subjects With Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3” NCT03834220
Target FGFR2 “A Phase II Basket Study of the Oral Selective Pan-FGFR Inhibitor Debio 1347 in Subjects With Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3” NCT03834220
Target FGFR3 “A Phase II Basket Study of the Oral Selective Pan-FGFR Inhibitor Debio 1347 in Subjects With Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3NCT03834220