Drugs / LB4330
last change Oct 2025 re-read 2 minutes ago

LB4330

Protein / enzyme biologic targets CLDN18

Developed for
cancer · cervical cancer
Investigated by
L & L Bio Co., Ltd., Ningbo, China · Shanghai East Hospital

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05707676 Nov 2022 → Dec 2024 cancer L & L Bio Co., Ltd., Ningbo, China Terminated No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT06468358 Jun 2024 → Dec 2026 expected cancer L & L Bio Co., Ltd., Ningbo, China Recruiting No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT07177716 Oct 2025 → Dec 2028 expected cervical cancer L & L Bio Co., Ltd., Ningbo, China Not yet recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as LB4330 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05707676
2

NCT07177716

NCT06468358

Action Activate “CD8 T cell activator” NCT05707676
Modality Protein / enzyme biologic “anti-Claudin 18.2 and CD8 T cell activator fusion protein” NCT05707676
Route Intravenous “LB4330 administered intravenously (IV)” NCT05707676
Target CLDN18 “anti-claudin18.2/IL-10 fusion protein” NCT06468358