Drugs / 212Pb-DOTAM-GRPR1
last change Jan 2023 re-read 3 minutes ago

212Pb-DOTAM-GRPR1

Other / unclassified targets GRPR via inhibition

Developed for
breast cancer · cervical cancer · colon carcinoma · glioblastoma · non-small cell lung carcinoma · prostate carcinoma
Investigated by
Orano Med Theranostics, SAS

Trials 1

20232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05283330 Dec 2022 → Jan 2027 expected breast cancer, cervical cancer, colon carcinoma, glioblastoma +2 Orano Med Theranostics, SAS Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as 212Pb-DOTAM-GRPR1 “212Pb-DOTAM-GRPR1 is a pharmaceutical radioimmunoconjugate consisiting of an α-particle-emitting radionuclide lead-212 (212Pb), a metal chelator DOTAM” PMID 36761980 ↗ Jan 2023
1

NCT05283330 ↗

Action Inhibit “a GRPR-targeted antagonist” NCT05283330 ↗
Modality Other / unclassified “is a pharmaceutical radioimmunoconjugate” PMID 36761980 ↗ Jan 2023
Target GRPR “a GRPR-targeted antagonist” NCT05283330 ↗