Drugs / ZAMAPORVINT
last change Apr 2024 re-read 2 minutes ago

ZAMAPORVINT

also known as RXC004

Small molecule targets PORCN via inhibition

Developed for
cancer · colorectal cancer
Investigated by
Redx Pharma Ltd · Merck Sharp & Dohme LLC

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03447470 Mar 2019 → Sep 2023 cancer Redx Pharma Ltd Completed No outcome recorded
Phase 22 trials
Phase 2 NCT04907851 Dec 2021 → Nov 2023 cancer Redx Pharma Ltd Completed No outcome recorded
Phase 2 NCT04907539 Nov 2021 → Apr 2024 colorectal cancer Redx Pharma Ltd Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as ZAMAPORVINT ChEMBL registry synonym — accepted as the source's own label CHEMBL5314431
Known as RXC004 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03447470
2

NCT04907539

NCT04907851

Action Inhibit inhibits porcupine (PORCN)” NCT03447470
Modality Small molecule CHEMBL5314431
Route Oral “RXC004 is taken orally” NCT03447470
Target PORCN “inhibits porcupine (PORCN)” NCT03447470